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Holy Shit - Working Cancer Vaccine!!

Posted: Mon Jun 20, 2011 10:28 am
by DerGolgo
http://io9.com/5813493/the-first-cancer ... that-works
Annalee Newitz on io9.com wrote:The researchers injected the mice with virus shells (the outer skin of viruses) packed with "libraries" of DNA made up partly of DNA taken from healthy prostate. The researchers believed that delivering the DNA inside viruses would essentially trick the mouse immune system, sending it into overdrive to produce antibodies tailor-made to attack cancers of the prostate. And their theory turned out to be correct. The mice produced antibodies which attacked their cancerous tumors, effectively eliminating the cancer. Because this vaccine's DNA libraries were tailor-made for prostate cancer, however, it also prevented the mice from producing antigens that attacked other organs in their bodies.
In other words: They made a virus that was sure to make the immune system go apeshit, and they made that virus so that any attack against it would also fuck-up the cancer cells. Immune system is set-off by the virus and takes down the cancer along with it.

In other words: Holy freaking shit!
I can only imagine a lot of molecular-geneticists and other experts of that ilk fiddling their beards and starting to think up what other ailments could be fought with such a technique...other cancers? Maybe persistent infections like hep-c?

I mean, for realz, they cured the cancer in these mice.
They didn't find some statistical significant reduction in occurence or tumor shrinkage or found some link to suggests there might be an anti-cancer mechanism here, they made the cancer go away.
That is 'effin momentous!

Okay, it'll fuck up social security, but still, this is outstanding! Amazing!
I just hope this isn't science by press-release overhyping something, but it sounds straightforward enough - cancer was made to go away.

Here's a more serious source: http://www.sciencedaily.com/releases/20 ... 133456.htm

And the research paper on nature.com (with paywall, unfortunately): http://www.nature.com/nm/journal/vaop/n ... .2390.html

Posted: Mon Jun 20, 2011 10:35 am
by red
One of two outcomes...

1. We will never see this for human use. It will get pushed aside like all the successful stem-cell research.

2. Zombies

Posted: Mon Jun 20, 2011 10:48 am
by Bigshankhank
They used ass cells.

And so the teenager in me took over for a few moments, and that's the best he could come up with. I am teh lame.

Posted: Mon Jun 20, 2011 12:41 pm
by xtian
3; all the people you love will be dead from cancer before it gets on the market.

Posted: Mon Jun 20, 2011 2:24 pm
by Toonce(s)
red wrote:2. Zombies
++

Experimental virus-based cure for cancer -> Zombie Apocalypse, every time.

Posted: Mon Jun 20, 2011 2:33 pm
by piccini9
Yup. Zombies, lots and lots of fuckin' ZOMBIES!

Really though, this is great news. :D

Posted: Mon Jun 20, 2011 2:47 pm
by red
piccini9 wrote:Yup. Zombies, lots and lots of fuckin' ZOMBIES!

Really though, this is great news. :D

Time to finally get that set of matching AR15s for me and the Mrs.

Posted: Tue Jun 21, 2011 11:50 am
by Beemer Dan
They'll never get Madagascar!

Seriously tho, this is pretty badass! It's about time we found a way give cancer the finger, and using a virus to do it? Damn groovy! I'm really skeptical of anything that screams "cure" for something as complex as cancer, but any good news on this front is really good news. Even if it turns out not to work in humans as it does in mice, it gives us a lot more information on the process.

I wonder if they'll be moving to human trials anytime soon?

Also, as you said DerGolgo, this could have a very big impact on the economy if it becomes widely available and affordable.

Posted: Tue Jun 21, 2011 11:53 am
by red
Beemer Dan wrote:They'll never get Madagascar!
Image


:mrgreen:

Posted: Tue Jun 21, 2011 12:37 pm
by UndertheGun
Bigshankhank wrote:They used ass cells.
Ass zombies.